December 1, 1978American Journal of Epidemiology
Diabetes Incidence and Prevalence in Pima Indians: A 19-Fold Greater Incidence Than in Rochester, Minnesota
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Discussion
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Implication
Longitudinal cohort study reveals extremely high diabetes rates in Pima Indians, indicating a nineteenfold higher incidence compared to general populations.
Key Points
- To assess the incidence and prevalence of diabetes mellitus over a 10-year follow-up period in Pima Indians.
- Followed 3,733 Pima Indians aged 5 years or older (N=3733) over a 10-year period with periodic examinations.
- Evaluated diabetes status using modified glucose tolerance tests and systematic reviews of medical records using stringent diagnostic criteria.
- The age-sex adjusted diabetes prevalence rate was 21.1% (SE = 0.7%), plateauing at 40% to 50% in adults older than 35 years.
- The age-sex adjusted incidence rate was 26.5 cases per 1,000 person-years (SE = 1.9), peaking at age 40 in males and age 50 in females.
- Diabetes incidence was 19-fold higher than in the population of Rochester, Minnesota (95% CI, 16 to 22).
Cite This Study
Knowler et al. (1978) studied this question.