Key result
Platelet serotonin levels were negatively correlated with impulsivity scores (P<0.05) in patients with recent self-destructive behavior, though this inverse relationship was only present in males.
Population
31 patients, >18 years old, with a recent history of human self-destructive behavior (HSDB)
Design
Cross-sectional
Authors
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Should not yet influence management of self-destructive behavior; leaves open a potential male-specific biomarker role pending longitudinal studies.
Observational (n=31)
p-value: p=<0.05
In patients with recent self-destructive behavior, platelet serotonin levels are low and inversely correlated with impulsivity in males.
Dutta et al. (2017) conducted an observational in Human self-destructive behavior (attempted suicide) (n=31). Platelet serotonin (5HT) levels and impulsivity was evaluated on Correlation between platelet serotonin levels and impulsivity scores (p=<0.05). Platelet serotonin levels were negatively correlated with impulsivity scores (P<0.05) in patients with recent self-destructive behavior, though this inverse relationship was only present in males.