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The aim is to evaluate how aging affects growth hormone secretion in men.

Effect of Age on Growth Hormone Secretion in Man

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The aim is to evaluate how aging affects growth hormone secretion in men.
Measured plasma GH levels in 44 men aged 22 to 81 years following an overnight fast.
Assessed responses to intravenous glucose and arginine infusions.
Estimated relative adipose content using weight and endogenous potassium emission measurements.
Plasma GH levels remained stable with age, showing no significant change after fasting, glucose pulse, or arginine infusion.
Increased relative adipose mass and fasting blood sugar were observed with age.
A diminished response to arginine in elderly subjects was noted, attributed to higher adipose mass.

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Randomized trial measures growth hormone levels across ages, indicating stability despite age-related changes.

Dudl et al. (1973) studied this question.

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