What question did this study set out to answer?

To investigate how sex and age influence GH secretion in response to GHRH in healthy individuals.

Effects of Sex and Age on Growth Hormone Response to Growth Hormone-Releasing Hormone in Healthy Individuals

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To investigate how sex and age influence GH secretion in response to GHRH in healthy individuals.
Studied 116 healthy individuals (women and men) aged 18-95 with specific BMI ranges.
Measured peak serum GH increments after GHRH administration and assessed age groups.
Conducted multiple regression analysis on GH responses correlated with hormone levels.
Premenopausal women showed higher peak GH increments than age-matched men (P<0.003 for 18-30 yr; P<0.03 for 30-50 yr).
Significant negative correlation between age and GHRH-induced GH responses in both sexes (P<0.001 for men; P<0.002 for women).
Positive correlation between estradiol levels and GH responses observed (P<0.01).

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Randomized trial uncovers how sex and age affect GH response in healthy individuals, suggesting notable differences in secretion patterns.

Lang et al. (1987) studied this question.

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Randomized trial uncovers how sex and age affect GH response in healthy individuals, suggesting notable differences in secretion patterns.