Why the study?
Are there sex differences in the management and outcomes of patients with acute stroke?
Population
44,832 patients discharged from acute-care hospitals in Ontario between April 1993 and March 1996 with a…
Comparison
Male sex vs Female sex
Design
Cohort
Follow-up
1 year
Key result
Female sex was associated with a lower risk of death 1 year after acute stroke compared to male sex (adjusted OR 0.939; 95% CI 0.899-0.980; P=0.004), despite men receiving more antiplatelets.
Authors
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Women show lower post-stroke mortality despite less antiplatelet use; leaves open whether sex-tailored care improves outcomes.
Cohort (n=44,832)
Yes
Are there sex differences in the management and outcomes of patients with acute stroke?
Effect estimate: adjusted OR 0.939 (95% CI 0.899 to 0.980)
p-value: p=0.004
Despite elderly men being more likely to receive antiplatelet therapy after a stroke, elderly women have a better 1-year survival.
Holroyd‐Leduc et al. (2000) conducted a cohort in acute stroke (n=44,832). Female sex vs. Male sex was evaluated on Risk of death 1 year after stroke (adjusted OR 0.939, 95% CI 0.899 to 0.980, p=0.004). Female sex was associated with a lower risk of death 1 year after acute stroke compared to male sex (adjusted OR 0.939; 95% CI 0.899-0.980; P=0.004), despite men receiving more antiplatelets.
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