Population
Conscious, unrestrained renovascular one-kidney, one clip (1K1C) rats
Comparison
Renal artery clipping evaluated at 1, 3, 7, 15… vs Sham rats
Design
Preclinical
Follow-up
60 days
Authors
Loading...
Attenuated baroreflex gain in this 1K1C rat model should not change clinical practice; leaves open sympathetic mechanisms for targeted hypertension research.
In a 1K1C hypertensive rat model, progressive attenuation of baroreceptor reflex sensitivity is primarily driven by a reduced contribution of the sympathetic component.
Moysés et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: