Key result
Low cholesterol in advanced heart failure is paradoxically associated with a poor prognosis, prompting examination of potential mechanisms and the awaited role of statin therapy in this population.
Population
Patients with advanced heart failure
Design
Review
Authors
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Does not support changing lipid management in advanced HF; leaves open statin efficacy pending randomized trials.
This review highlights the cholesterol paradox in advanced heart failure and anticipates results from large trials evaluating statin therapy in this population.
Velavan et al. (2007) conducted a review in Heart failure. Statins was evaluated. Low cholesterol in advanced heart failure is paradoxically associated with a poor prognosis, prompting examination of potential mechanisms and the awaited role of statin therapy in this population.
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