Why the study?
Does valsartan reduce blood pressure compared to enalapril or placebo in adult outpatients with mild-to-moderate uncomplicated essential hypertension?
Does valsartan reduce blood pressure compared to enalapril or placebo in adult outpatients with mild-to-moderate uncomplicated essential hypertension?
Valsartan 80 mg daily provides comparable antihypertensive efficacy to enalapril 20 mg daily in mild-to-moderate hypertension, with excellent tolerability.
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Supports valsartan as an effective alternative to enalapril; confirms ARB-ACEI equivalence for BP lowering in mild-to-moderate hypertension.
Holwerda et al. (1996) studied this question.
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