Key result
Whole blood viscosity values at both shear rates were significant and independent predictors for early LV apical thrombus formation after a first acute anterior myocardial infarction.
Why the study?
The study sought to investigate the predictive value of whole blood viscosity to identify high-risk patients who will develop an apical thrombus during the acute phase of anterior transmural infarction.
Does whole blood viscosity predict early LV apical thrombus formation in patients with first acute anterior myocardial infarction?
Observational (n=1,726)
Does whole blood viscosity predict early LV apical thrombus formation in patients with first acute anterior myocardial infarction?
Whole blood viscosity calculated by Simone's formula can independently predict the formation of early LV apical thrombus in patients with first acute anterior myocardial infarction.
Answers are grounded in this paper and cite their sources.
May aid risk stratification for apical thrombus after anterior MI; leaves open whether viscosity modification improves outcomes.
Aim: This study sought to investigate the predictive value of whole blood viscosity (WBV) to identify high-risk patients who will develop an apical thrombus during the acute phase of anterior transmural infarction. Materials & methods: Consecutive 1726 patients with first acute anterior myocardial infarction were evaluated. WBV was calculated according to the Simone’s formula. Results: Patients with an apical thrombus had prolonged pain to balloon time, higher rate of post-PCI thrombolysis in myocardial infarction flow ≤1 and significantly higher mean WBV values at both shear rates than those without an apical thrombus. Conclusion: WBV values at both shear rates were found to be significant and independent predictors for early LV apical thrombus formation complicating a first-ever anterior wall myocardial infarction.
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Tak et al. (2020) conducted an observational in Acute anterior myocardial infarction (n=1,726). Whole blood viscosity (WBV) was evaluated on Early LV apical thrombus formation. Whole blood viscosity values at both shear rates were significant and independent predictors for early LV apical thrombus formation after a first acute anterior myocardial infarction.
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