Key result
Excellent adherence to antihypertensive therapy significantly reduced the risk of all-cause death, stroke, or acute myocardial infarction compared with poor adherence (HR 0.53, P<0.001).
Why the study?
Does good or excellent adherence to antihypertensive therapy reduce the risk of all-cause mortality, stroke, or acute myocardial infarction compared to poor adherence in newly treated hypertensive patients?
Population
31,306 adults newly treated with antihypertensive therapy for primary prevention of cardiovascular disease…
Comparison
Good or excellent adherence to antihypertensive… vs Poor adherence to antihypertensive therapy
Design
Cohort
Authors
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Supports adherence promotion in new hypertension; leaves open whether RCTs confirm causality before practice change.
Cohort (n=31,306)
No
Does good or excellent adherence to antihypertensive therapy reduce the risk of all-cause mortality, stroke, or acute myocardial infarction compared to poor adherence in newly treated hypertensive patients?
Effect estimate: HR 0.53
p-value: p=<0.001
Good and excellent adherence to antihypertensive therapy in primary prevention significantly reduces the risk of all-cause mortality, stroke, and acute myocardial infarction compared to poor adherence.
Luca Degli Esposti (2011) conducted a cohort in Hypertension (n=31,306). Antihypertensive therapy (excellent adherence) vs. Poor adherence was evaluated on all-cause mortality, stroke, or acute myocardial infarction (HR 0.53, p=<0.001). Excellent adherence to antihypertensive therapy significantly reduced the risk of all-cause death, stroke, or acute myocardial infarction compared with poor adherence (HR 0.53, P<0.001).
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