Key result
Phylogenetic analysis of 105 foot-and-mouth disease type O viruses identified eight major genetic lineages (topotypes) that fall within distinct geographical boundaries.
Population
105 foot-and-mouth disease type O viruses obtained from samples submitted to the OIE/FAO World Reference…
Design
Preclinical
Authors
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Supports regional FMD surveillance; leaves open validation for vaccine matching and transmission modeling.
FMD type O viruses can be classified into eight distinct evolutionary lineages (topotypes) that correlate with geographical boundaries.
Samuel et al. (2001) studied Foot-and-mouth disease (FMD) type O viruses (n=105). Phylogenetic analysis was evaluated on Identification of major genotypes based on nucleotide sequences at the 3' end of the VP1 gene. Phylogenetic analysis of 105 foot-and-mouth disease type O viruses identified eight major genetic lineages (topotypes) that fall within distinct geographical boundaries.
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