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September 1, 1998International ImmunologyOpen Access

Age-related modifications of the human alphabeta T cell repertoire due to different clonal expansions in the CD4+ and CD8+ subsets

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Authors

AWAndreas WackThe Francis Crick Institute

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Andreas Wack (1998) studied this question.

synapsesocial.com/papers/6a129c4cd83a8a9cd0a3eeb1https://doi.org/10.1093/intimm/10.9.1281
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  1. 1H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity.1992 · 99 citations
  2. 2Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.1988 · 928 citations
  3. 3Clonal predominance of T cell receptors within the CD8+ CD45RO+ subset in normal human subjects.1993 · 288 citations