Key result
Door-to-balloon time <45 min in STEMI is linked to ~47% lower 3-year major event risk.
Why the study?
The impact of shorter door-to-balloon time on long-term clinical outcomes in patients with STEMI treated with primary PCI had not been fully elucidated.
Does shorter door-to-balloon time improve long-term clinical outcomes in STEMI patients treated with primary PCI?
Cohort (n=1,639)
Yes
Does shorter door-to-balloon time improve long-term clinical outcomes in STEMI patients treated with primary PCI?
Shorter door-to-balloon time is associated with significantly better long-term clinical outcomes up to 3 years in STEMI patients undergoing primary PCI.
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Nishio et al. (2023) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=1,639). Door-to-balloon time < 45 min vs. Door-to-balloon time > 90 min was evaluated on Composite of all-cause death, non-fatal MI, non-fatal stroke, cardiac failure, and urgent revascularization for unstable angina up to 3 years (p=0.0129). Shorter door-to-balloon time (<45 min) in STEMI patients undergoing PPCI was associated with a lower 3-year primary composite endpoint rate (10.2% vs 15.3%, 16.2%, and 19.3%; p=0.0129).
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