Key result
Percutaneous coronary intervention at high-volume centers significantly reduced the likelihood of delayed door-to-balloon time >90 minutes compared to low-volume centers (OR 0.42).
Observational (n=2,428)
Yes
Odds Ratio: 0.42 (95% CI 0.32–0.55)
p-value: p=<0.001
In a contemporary Japanese registry, half of STEMI patients failed to achieve a door-to-balloon time ≤90 minutes, highlighting the need to target off-hour presentations and complex patients.
BACKGROUND: Door-to-balloon (DTB) time ≤90 min is an important quality indicator in the management of ST-elevation myocardial infarction (STEMI), but a considerable number of patients still do not meet this goal, particularly in countries outside the USA and Europe. METHODS AND RESULTS: We analyzed 2,428 STEMI patients who underwent primary PCI ≤12 h of symptom onset who were registered in an ongoing prospective multicenter database (JCD-KiCS registry), between 2008 and 2013. We analyzed both the time trend in DTB time within this cohort in the registry, and independent predictors of delayed DTB time >90 min. Median DTB time was 90 min (IQR, 68-115 min) during the study period and there were no significant changes with year. Predictors for delay in DTB time included peripheral artery disease, prior revascularization, off-hour arrival, age >75 years, heart failure at arrival, and use of IABP or VA-ECMO. Notably, high-volume PCI-capable institutions (PCI ≥200/year) were more adept at achieving shorter DTB time compared with low-volume institutions (PCI <200/year). CONCLUSIONS: Half of the present STEMI patients did not achieve DTB time ≤90 min. Targeting the elderly and patients with multiple comorbidities, and PCI performed in off-hours may aid in its improvement.
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Ikemura et al. (2017) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=2,428). PCI at high-volume centers (≥200/year) vs. PCI at low-volume centers (<200/year) was evaluated on Delayed door-to-balloon (DTB) time >90 min (OR 0.42, 95% CI 0.32-0.55, p=<0.001). Percutaneous coronary intervention at high-volume centers significantly reduced the likelihood of delayed door-to-balloon time >90 minutes compared to low-volume centers (OR 0.42).
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