Key result
Managing PE with RV involvement requires prompt integration of hemodynamic, reperfusion, pharmacologic, and mechanical support.
Why the study?
Pulmonary embolism significantly impacts right-sided heart function, with clinical presentations ranging from no right ventricular involvement to right ventricular dysfunction, cardiogenic shock, and cardiac arrest.
This review emphasizes that managing right ventricular failure in acute pulmonary embolism requires early risk stratification and a multidisciplinary approach combining reperfusion, hemodynamic support, and advanced therapies.
Answers are grounded in this paper and cite their sources.
Supports multidisciplinary PE care with RV involvement; leaves open prospective trials to standardize protocols and device selection.
Pulmonary embolism (PE) has a significant impact on right-sided heart function. Clinical presentation can range from no involvement of the right ventricle to right ventricular dysfunction, cardiogenic shock, and even cardiac arrest. The authors explore the pathophysiology of PE-induced right ventricular failure, emphasizing the mechanisms by which PE contributes to dysfunction, current diagnostic tools for risk stratification, and the importance of timely diagnosis. The primary focus is on strategies for managing right ventricular failure secondary to PE, including medical, percutaneous interventional, and surgical options. Recent advances in the field are also noted, including emerging therapies and evolving treatment algorithms.
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Sorathia et al. (2025) conducted a review in Right ventricular failure in the setting of pulmonary embolism. Management of pulmonary embolism with right ventricular involvement requires prompt integration of hemodynamic management, reperfusion, pharmacologic support, and mechanical circulatory support.
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