Key result
Patients with obstructive sleep apnoea were 5.9 times more likely to have metabolic syndrome compared to non-OSA patients, independent of obesity, but were not significantly more insulin resistant.
Why the study?
Is obstructive sleep apnoea independently associated with metabolic syndrome and insulin resistance in patients referred for suspected sleep apnoea?
Cross-Sectional (n=79)
No
Is obstructive sleep apnoea independently associated with metabolic syndrome and insulin resistance in patients referred for suspected sleep apnoea?
Effect estimate: OR 5.9 (95% CI 2.0-17.6)
Absolute Event Rate: 74% vs 24%
p-value: p=<0.001
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OSA associated with metabolic syndrome independent of obesity but not insulin resistance; leaves open causal role and screening utility.
Gruber et al. (2006) conducted a cross-sectional in Obstructive sleep apnoea (n=79). Obstructive sleep apnoea vs. Non-obstructive sleep apnoea controls was evaluated on Prevalence of metabolic syndrome (OR 5.9, 95% CI 2.0-17.6, p=<0.001). Patients with obstructive sleep apnoea were 5.9 times more likely to have metabolic syndrome compared to non-OSA patients, independent of obesity, but were not significantly more insulin resistant.
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