Key result
Oral digoxin significantly improved left ventricular ejection fraction from 0.36 to 0.45 (P<0.01) in elderly patients with congestive heart failure or cardiomegaly in sinus rhythm.
Why the study?
Does oral digoxin improve left ventricular ejection fraction in elderly patients with congestive heart failure or cardiomegaly in sinus rhythm?
Observational (n=20)
Does oral digoxin improve left ventricular ejection fraction in elderly patients with congestive heart failure or cardiomegaly in sinus rhythm?
p-value: p=<0.01
Oral digoxin significantly improves left ventricular ejection fraction in elderly patients with heart failure in sinus rhythm, with maximal benefit often seen at low serum concentrations (0.4-1.0 ng/ml).
No takes yet. Share an insight, caveat, or question.
May support digoxin for LVEF gains in elderly sinus-rhythm HF; leaves open confirmation by RCTs before practice change.
Ware et al. (1984) conducted an observational in Congestive heart failure or cardiomegaly (n=20). Oral digoxin vs. No digoxin was evaluated on Left ventricular ejection fraction (p=<0.01). Oral digoxin significantly improved left ventricular ejection fraction from 0.36 to 0.45 (P<0.01) in elderly patients with congestive heart failure or cardiomegaly in sinus rhythm.
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