August 1, 1988European Heart Journal
Reproducibility of Doppler echocardiographic measurements of left ventricular diastolic function
Key result
Doppler echocardiographic indexes of early diastolic events showed small variability, whereas indexes of late diastolic events showed significantly greater day-to-day variability (P<0.05).
Why the study?
What is the reproducibility of Doppler echocardiographic measurements of left ventricular diastolic function in normal subjects?
Population
12 normal subjects
Design
Other
Authors
Discussion
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Implication
Late diastolic Doppler indexes warrant cautious clinical interpretation; leaves open standardization of diastolic assessments in future research.
Key Points
- This investigation aims to evaluate the technical and biological variability of Doppler indexes related to diastolic function in healthy individuals.
- Assessed six validated Doppler indexes of diastolic function in 12 normal subjects.
- Compared variability due to the reader, technician, and day-to-day variations.
- Analyzed both early and late diastolic events using Doppler measurements.
- Day-to-day variability was greater than variability due to the reader or technician in 21 of 24 comparisons.
- The early diastolic Doppler indexes showed small variability, without significant changes over days.
- Late diastolic indexes exhibited greater variability, highlighting the need for cautious interpretation of atrial contribution to filling.
Study Design
Type
Observational (n=12)
Structured PICO
What is the reproducibility of Doppler echocardiographic measurements of left ventricular diastolic function in normal subjects?
P
Population
12 normal subjects
I
Intervention
Doppler echocardiographic measurements of left ventricular diastolic function (six previously validated indexes)
O
Outcome
Magnitude of technical and biologic variability (reader, technician, and day-to-day) of six Doppler indexes of diastolic functionsurrogate
Main Result
p-value: p=<0.05
Doppler echocardiographic indexes of early diastolic filling are highly reproducible, whereas indexes of late (atrial) filling show significant day-to-day variability and should be interpreted with caution.
Cite This Study
Spirito et al. (1988) conducted an observational in Normal subjects (n=12). Doppler echocardiographic measurements was evaluated on Magnitude of technical and biologic variability of six Doppler indexes of diastolic function (p=<0.05). Doppler echocardiographic indexes of early diastolic events showed small variability, whereas indexes of late diastolic events showed significantly greater day-to-day variability (P<0.05).