Key result
Two weeks of muscle immobilization impaired functional sympatholysis and increased exercise leg blood flow (2.9 vs 2.6 l/min; P<0.05) and vasodilatory response to infused ATP compared to control.
Authors
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Hypothesis-generating for disuse effects on vascular control; leaves open clinical relevance for rehabilitation or exercise responses.
Absolute Event Rate: 2.9% vs 2.6%
p-value: p=<0.05
Mortensen et al. (2012) studied Healthy volunteers (n=8). One-legged knee-extensor training and immobilization vs. Control leg was evaluated on Leg blood flow (LBF) during exercise (p=<0.05). Two weeks of muscle immobilization impaired functional sympatholysis and increased exercise leg blood flow (2.9 vs 2.6 l/min; P<0.05) and vasodilatory response to infused ATP compared to control.
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