Key result
Direct TAVI without pre-implantation balloon aortic valvuloplasty is discussed as a feasible and safe alternative to standard TAVI, though high-quality robust evidence is currently lacking.
Why the study?
Does direct TAVI (without predilatation) provide similar safety and outcomes compared to standard TAVI with predilatation in patients undergoing TAVI?
Does direct TAVI (without predilatation) provide similar safety and outcomes compared to standard TAVI with predilatation in patients undergoing TAVI?
Answers are grounded in this paper and cite their sources.
Direct TAVI without predilatation appears feasible and safe, offering a simplified procedure, though high-quality randomized evidence is currently lacking.
Predilatation has been historically considered a mandatory step before transcatheter aortic valve implantation (TAVI) since it facilitates valve crossing and prosthesis delivery, ensures optimal valve expansion and improves hemodynamic stability during valve deployment. However, as a result of procedural evolution over time, direct TAVI (without pre-implantation balloon aortic valvuloplasty) has emerged as an interesting option to simplify the procedure and to avoid potential valvuloplasty-related complications. Several real-world retrospective studies and one small randomised study have shown that direct TAVI (with both self-expanding and balloon-expandable prostheses) is feasible, safe and associated with outcomes similar to standard TAVI with pre-implantation balloon aortic valvuloplasty. In the absence of high-quality, robust evidence, the current review aims to discuss the advantages and disadvantages of omitting predilatation prior to TAVI.
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Pagnesi et al. (2017) conducted a review in Aortic stenosis undergoing TAVI. Direct TAVI (without predilatation) vs. Standard TAVI with predilatation was evaluated. Direct TAVI without pre-implantation balloon aortic valvuloplasty is discussed as a feasible and safe alternative to standard TAVI, though high-quality robust evidence is currently lacking.
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