Key result
Transcatheter aortic valve implantation without predilatation achieved a 96.3% technical success rate and preserved left ventricular function without transient impairment.
Why the study?
Prior studies observed transient LV function decrease and elevated myocardial injury markers after TAVI with predilatation, prompting investigation into whether direct TAVI causes similar biomarker increases and EF decrease.
Does TAVI without predilatation reduce markers of myocardial injury and preserve left ventricular function in symptomatic patients with severe aortic stenosis?
Population
164 consecutive patients undergoing TAVI without predilatation using a self-expanding system
Comparison
TAVI without predilatation (direct TAVI)
Design
Single-center retrospective cohort study
Follow-up
One year
Authors
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Direct TAVI may limit myocardial injury; leaves open outcome benefits versus standard approaches in randomized trials.
Cohort (n=164)
No
Does TAVI without predilatation reduce markers of myocardial injury and preserve left ventricular function in symptomatic patients with severe aortic stenosis?
Direct TAVI without balloon predilatation is feasible and safe, maintaining left ventricular function and potentially causing less myocardial injury than traditional TAVI with predilatation.
Mirna et al. (2020) conducted a cohort in Aortic valve stenosis (n=164). Transcatheter aortic valve implantation (TAVI) without predilatation was evaluated on Technical success rate according to VARC-2 criteria. Transcatheter aortic valve implantation without predilatation achieved a 96.3% technical success rate and preserved left ventricular function without transient impairment.
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