Key result
Omitting predilation in balloon-expandable TAVI is linked to ~57% lower 30-day mortality and shorter procedures.
Why the study?
The effect of omitting predilation on feasibility, procedural results, and safety in balloon-expandable TAVI was not well established.
Does the omission of predilation improve procedural outcomes and safety in patients undergoing balloon-expandable TAVI?
Population
680 patients scheduled for balloon-expandable TAVI prosthesis
Comparison
Balloon-expandable TAVI without predilation vs with predilation
Design
Retrospective analysis in a large-volume centre
Follow-up
30 days
Authors
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May favor omitting predilation in balloon-expandable TAVI; leaves open confirmation in randomized trials.
Cohort (n=680)
No
Does the omission of predilation improve procedural outcomes and safety in patients undergoing balloon-expandable TAVI?
Absolute Event Rate: 2.9% vs 6.8%
p-value: p=0.03
Omitting predilation in balloon-expandable TAVI is feasible and associated with shorter procedure times, less contrast use, and lower 30-day mortality compared to routine predilation.
Hamm et al. (2017) conducted a cohort in Scheduled for balloon-expandable TAVI (n=680). Omission of predilation vs. TAVI with predilation (prior valvuloplasty) was evaluated on 30-day all-cause mortality (p=0.03). Omission of predilation during balloon-expandable TAVI was associated with lower 30-day all-cause mortality (2.9% vs 6.8%, p=0.03) and shorter procedure times compared to prior valvuloplasty.
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