Why the study?
What baseline variables predict response to renal denervation in patients with resistant arterial hypertension?
Population
Patients with resistant arterial hypertension (RAH) after exclusion of secondary causes
Design
Cohort
Follow-up
12 months
Key result
Renal denervation resulted in a response (≥5 mmHg 24h SBP drop) in 45.6% of patients with resistant hypertension at 6 months, with higher baseline SBP and more antihypertensive drugs predicting response.
Authors
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Baseline predictors may guide renal denervation selection in resistant hypertension; hypothesis-generating and requires randomized confirmation.
Observational
What baseline variables predict response to renal denervation in patients with resistant arterial hypertension?
Elevated baseline systolic blood pressure, BMI, and number of antihypertensive drugs predict a greater blood pressure reduction following renal denervation in resistant hypertension.
Rohla et al. (2015) conducted an observational in Resistant arterial hypertension. Renal denervation (RDN) vs. None was evaluated on Response defined as at least 5 mmHg 24 h SBP drop at 6 months. Renal denervation resulted in a response (≥5 mmHg 24h SBP drop) in 45.6% of patients with resistant hypertension at 6 months, with higher baseline SBP and more antihypertensive drugs predicting response.