Why the study?
Does antihypertensive treatment reduce ambulatory blood pressure and blood pressure variability in mild essential hypertensive outpatients?
Population
266 mild essential hypertensive outpatients (age: 18-78 years)
Comparison
Antihypertensive treatment with an ACE-inhibitor… vs Pre-treatment baseline
Design
Cohort
Follow-up
4 to 8 weeks
Authors
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Clinic BP changes unreliable for predicting ambulatory responses; leaves open whether routine ambulatory monitoring is needed to assess treatment effects.
Does antihypertensive treatment reduce ambulatory blood pressure and blood pressure variability in mild essential hypertensive outpatients?
Antihypertensive treatment effectively reduces ambulatory blood pressure, but this reduction cannot be reliably predicted by changes in clinic blood pressure.
Mancia et al. (1995) studied this question.
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