Key result
A new volume-clamping method preserving the native mitral valve successfully maintained left ventricular volume near end-systolic volume throughout diastole without disturbing native valve movement.
Why the study?
Does a new volume-clamping method preserving the native mitral valve maintain constant LV volume during diastole compared to the traditional bypass method in dogs?
Does a new volume-clamping method preserving the native mitral valve maintain constant LV volume during diastole compared to the traditional bypass method in dogs?
A new volume-clamping method in dogs successfully maintains constant LV volume during diastole while preserving the native mitral valve and avoiding cardiopulmonary bypass.
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May enable diastolic LV studies in intact canine valves; leaves open translation to human physiology.
Ohtani et al. (1991) studied Left ventricular volume clamping (animal model) (n=9). New volume-clamping method preserving native mitral valve without cardiopulmonary bypass vs. Method of Yellin et al. (replacing mitral valve using cardiopulmonary bypass) was evaluated on Hemodynamic performance and left ventricular volume maintenance. A new volume-clamping method preserving the native mitral valve successfully maintained left ventricular volume near end-systolic volume throughout diastole without disturbing native valve movement.
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