Key result
Microalbuminuria affects ~36% of hypertensive patients and is linked to frequent target organ damage.
Why the study?
Microalbuminuria is an independent risk factor associated with fatal cardiovascular and cerebrovascular outcomes in hypertensive patients, motivating an assessment of its frequency and relationship to target organ damage.
Cross-Sectional (n=100)
No
Answers are grounded in this paper and cite their sources.
In a cross-sectional study of hypertensive patients in India, microalbuminuria was present in 36% of patients and was strongly associated with target organ damage such as diastolic dysfunction and hypertensive retinopathy.
Background: Microalbuminuria (MA) is an independent risk factor in association with fatal cardiovascular and cerebrovascular outcomes among patients with hypertension (HTN). Methods: An observational study was conducted among 100 randomly selected hypertensive patients January 2013 to January 2014 to observe the proportion of MA among hypertensive patients and the proportion of presence of various target organ damages (TODs) in them. Results: The frequency of MA was 36% among participants. The frequency in males was slightly more than females (38.2% vs. 33.3%). The frequency of MA increased linearly with the duration and severity of HTN. It was more commonly found in smokers than in non-smokers. Diastolic dysfunction (42%) and Grade 2 hypertensive retinopathy (60.7%) were associated with MA. TOD was frequently observed in MA-positive patients. Conclusions: The proportion of patients with MA was in increasing trend with increasing age of hypertensive participants and duration of history of HTN. Hypertensive retinopathy, regional wall motion abnormality and neurological deficit emerged to be sensitive surrogate markers for MA in patients with HTN.
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Bhowmick et al. (2023) conducted a cross-sectional in Hypertension (n=100). Microalbuminuria was evaluated on Proportion of microalbuminuria and presence of various target organ damages. Microalbuminuria was present in 36% of hypertensive patients and was frequently associated with target organ damage, including diastolic dysfunction (42%) and Grade 2 hypertensive retinopathy (60.7%).
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