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September 17, 2020Pacing and Clinical Electrophysiology

The subcutaneous ICD for prevention of sudden cardiac death: Current evidence and future directions

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Key result

S-ICDs provide a valid alternative to TV-ICDs for patients not requiring bradycardia pacing or CRT.

Why the study?

Sudden cardiac death remains an important cause of cardiovascular mortality, motivating the development and evolution of the totally subcutaneous ICD to improve upon the risk-benefit balance of transvenous ICD systems.

Does the subcutaneous ICD provide a safe and effective alternative to transvenous ICDs for the prevention of sudden cardiac death in patients not requiring pacing?

Population

Patients with an ICD indication not requiring bradycardia pacing or cardiac resynchronization therapy

Comparison

Subcutaneous ICD vs transvenous ICD systems

Design

Review

Authors

JSJan Steffel

Discussion

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Overview

Supports S-ICD consideration in non-pacing patients; leaves open need for randomized comparative trials.

Structured PICO

Does the subcutaneous ICD provide a safe and effective alternative to transvenous ICDs for the prevention of sudden cardiac death in patients not requiring pacing?

P
Population
Patients with an ICD indication in whom bradycardia pacing or cardiac resynchronization therapy is not required
I
Intervention
Subcutaneous implantable cardioverter-defibrillator (S-ICD)
C
Comparator
Transvenous implantable cardioverter-defibrillators (TV-ICD)
O
Outcome
Efficacy and safety (prevention of sudden cardiac death and system-related problems)

The S-ICD is a valid and potentially safer alternative to transvenous ICDs for preventing sudden cardiac death in patients who do not need pacing or CRT.

Cite This Study

Jan Steffel (2020) conducted a review in Sudden cardiac death. Subcutaneous ICD (S-ICD) vs. Transvenous ICDs was evaluated. Current generation subcutaneous ICD systems are a valid alternative to transvenous ICDs in patients with an ICD indication not requiring bradycardia pacing or cardiac resynchronization therapy.

synapsesocial.com/papers/6a15383c814bf8ec9a4e415ahttps://doi.org/10.1111/pace.14066
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Spotlight on S-ICD™ therapy: 10 years of clinical experience and innovation2019 · 28 citations
  2. 2Worldwide experience with a totally subcutaneous implantable defibrillator: early results from the EFFORTLESS S-ICD Registry2014 · 463 citations
  3. 3Low Prevalence of Inappropriate Shocks in Patients With Inherited Arrhythmia Syndromes With the Subcutaneous Implantable Defibrillator Single Center Experience and Long‐Term Follow‐Up2017 · 38 citations
  4. 4Subcutaneous or Transvenous Defibrillator Therapy2020 · 480 citations
  5. 5Six‐year follow‐up of the initial Dutch subcutaneous implantable cardioverter‐defibrillator cohort: Long‐term complications, replacements, and battery longevity2018 · 47 citations