What does this research mean for the field?

Patients with congestive cardiomyopathy exhibit normal cell-mediated immunity to common environmental antigens and mitogens at the time of clinical presentation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Determine whether patients presenting with congestive cardiomyopathy exhibit normal or depressed cell-mediated immunity against common antigens and mitogens.

April 1, 1985HeartOpen Access

Cellular immunity in congestive cardiomyopathy. The normal cellular immune response.

View Full Paper

Ask AI

Bookmark

Why the study?

Do patients with congestive cardiomyopathy have normal or depressed cell mediated immunity to common environmental antigens and mitogens?

Population

Patients with congestive cardiomyopathy

Design

Cross-sectional

Authors

PLP J LowryUniversity of Reading RTR A ThompsonOregon Health & Science University WLW. A. LittlerNIHR Surgical Reconstruction and Microbiology Research Centre

Discussion

Member takes

Implication

Preserved cell-mediated immunity at presentation in congestive cardiomyopathy; leaves open longitudinal or prognostic implications.

Key Points

Determine whether patients presenting with congestive cardiomyopathy exhibit normal or depressed cell-mediated immunity against common antigens and mitogens.
Assessed cellular immunity in patients diagnosed with congestive cardiomyopathy.
Performed in vivo and in vitro immune function tests challenged with common environmental antigens and mitogens.
No cellular immune abnormalities were detected in congestive cardiomyopathy patients across testing panels.
Findings suggest cell-mediated immunity is normal at clinical presentation, though transient immune depression during early subclinical stages remains possible.

Structured PICO

Do patients with congestive cardiomyopathy have normal or depressed cell mediated immunity to common environmental antigens and mitogens?

Population

Patients with congestive cardiomyopathy

Outcome

Cell mediated immunity to common environmental antigens and mitogenssurrogate

Patients with congestive cardiomyopathy demonstrate normal cell-mediated immunity to common environmental antigens and mitogens at clinical presentation.

Limitations

Does not exclude the possibility that transient depression of cell mediated mechanisms occurs early in the illness before clinical presentation

Cite This Study

Lowry et al. (1985) studied this question.

synapsesocial.com/papers/6a153bc35347fbb1739f71f0 https://doi.org/10.1136/hrt.53.4.394

Topics

Heart failure HFrEF treatment

View Full Paper

Ask AI

Bookmark

Cellular immunity in congestive cardiomyopathy. The normal cellular immune response.

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Topics

Cellular immunity in congestive cardiomyopathy. The normal cellular immune response.

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider