Key result
A pharmacist intervention significantly increased the average number of appropriate weight-titrated frusemide dose adjustments per patient per month compared to usual care (0.85 vs 0.32; p=0.006).
Why the study?
Does a pharmacist intervention improve appropriate weight-titrated frusemide dose adjustments in ambulatory patients with heart failure?
Population
70 ambulatory patients with heart failure
Comparison
Pharmacist intervention added to usual care for… vs Usual care
Design
RCT, Randomised
Follow-up
3 months
Authors
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Supports pharmacist integration for HF diuretic titration; extends collaborative care evidence in ambulatory settings.
RCT (n=70)
randomised
Does a pharmacist intervention improve appropriate weight-titrated frusemide dose adjustments in ambulatory patients with heart failure?
Absolute Event Rate: 0.85% vs 0.32%
p-value: p=0.006
A pharmacist-led intervention significantly improved heart failure patients' ability to self-adjust diuretic doses, leading to improved quality of life and fewer hospital readmissions for fluid overload.
Korajkic et al. (2011) conducted an RCT in heart failure (n=70). Pharmacist intervention (self-care, symptom recognition, daily weight, self-adjusting frusemide) vs. Usual care was evaluated on Number of appropriate weight-titrated frusemide dose adjustments per patient per month (p=0.006). A pharmacist intervention significantly increased the average number of appropriate weight-titrated frusemide dose adjustments per patient per month compared to usual care (0.85 vs 0.32; p=0.006).
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