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April 1, 1988Annual Review of ImmunologyOpen Access

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

Hans Clevers Balbino Alarcón Thomas Wileman Cox Terhorst

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Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...

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Clevers et al. (1988) studied this question.

synapsesocial.com/papers/6a154c9c79ff98d0de4e677f https://doi.org/10.1146/annurev.iy.06.040188.003213

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