Key result
CRT implantation in AF is associated with ~86% five-year sinus rhythm maintenance in paroxysmal cases.
Why the study?
Atrial fibrillation is highly prevalent in heart failure patients undergoing CRT, but whether an atrial lead should be implanted in these patients remains unclear.
Does CRT implantation with an atrial lead improve sinus rhythm conversion and maintenance in patients with heart failure and atrial fibrillation?
Population
328 consecutive patients with a history of AF receiving CRT implantation
Comparison
Patients with paroxysmal vs persistent vs long-standing persistent AF
Design
Retrospective observational cohort study
Follow-up
5 years
Authors
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CRT with atrial lead linked to high SR maintenance in HF-AF; hypothesis-generating, needs RCTs before practice change.
Cohort (n=328)
No
Does CRT implantation with an atrial lead improve sinus rhythm conversion and maintenance in patients with heart failure and atrial fibrillation?
CRT implantation with an atrial lead is associated with high rates of long-term sinus rhythm maintenance in patients with heart failure and atrial fibrillation, supporting routine atrial lead implantation in this population.
Ziegelhoeffer et al. (2020) conducted a cohort in Atrial fibrillation in heart failure patients (n=328). Cardiac resynchronization therapy (CRT) implantation with an atrial lead was evaluated on Sinus rhythm conversion and maintenance. CRT implantation in patients with atrial fibrillation achieved 5-year sinus rhythm maintenance rates of 85.7% for paroxysmal, 69.7% for persistent, and 44.1% for long-standing persistent AF.
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