Key result
Right ventricular pressure overload in pulmonary hypertension reduced RV lateral wall longitudinal strain compared to healthy controls (-15.9% vs -25.5%, P<0.001) and impaired LV torsion.
Why the study?
Does pulmonary hypertension alter right and left ventricular geometry, strain, and rotational mechanics compared to healthy controls?
Population
44 patients with evidence of pulmonary hypertension, age 46+/-12 years, 82% women, excluding intrinsic LV…
Design
Case-control
Authors
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RV strain and torsion changes in PH may refine echo assessment; leaves open prognostic integration pending prospective validation.
Case-Control (n=88)
Does pulmonary hypertension alter right and left ventricular geometry, strain, and rotational mechanics compared to healthy controls?
Absolute Event Rate: -15.9% vs -25.5%
p-value: p=<0.001
Chronic right ventricular pressure overload in pulmonary hypertension directly impairs RV longitudinal systolic deformation and further alters LV geometry and torsion.
Puwanant et al. (2010) conducted a case-control in Pulmonary Hypertension (n=88). Right ventricular pressure overload vs. Healthy subjects was evaluated on Right ventricular lateral wall longitudinal strain (p=<0.001). Right ventricular pressure overload in pulmonary hypertension reduced RV lateral wall longitudinal strain compared to healthy controls (-15.9% vs -25.5%, P<0.001) and impaired LV torsion.
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