Key result
Mild elevation in pulmonary artery systolic pressures resulted in lower peak longitudinal RV free wall strain (-27.3% vs. -31.9%, P<0.04) and significant RV dyssynchrony (-83 ms vs. 1 ms, P<0.00001).
Why the study?
Do mild elevations in pulmonary artery systolic pressure affect right ventricular mechanical properties and dyssynchrony?
Population
40 patients divided into two groups based on pulmonary artery systolic pressures. Group I: mean age 48 +/…
Design
Cross-sectional
Authors
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May support early RV strain monitoring in mild PASP elevation; hypothesis-generating and requires prospective validation before practice change.
Cross-Sectional (n=40)
Do mild elevations in pulmonary artery systolic pressure affect right ventricular mechanical properties and dyssynchrony?
Absolute Event Rate: -27.3% vs -31.9%
p-value: p=<0.04
Mild elevations in pulmonary artery systolic pressure are associated with abnormal right ventricular mechanical properties and dyssynchrony, even before gross abnormalities in RV size or function appear.
López‐Candales et al. (2007) conducted a cross-sectional in Mild pulmonary hypertension (n=40). Mild elevation in PASP vs. Normal PASP was evaluated on Peak longitudinal RV free wall strain (p=<0.04). Mild elevation in pulmonary artery systolic pressures resulted in lower peak longitudinal RV free wall strain (-27.3% vs. -31.9%, P<0.04) and significant RV dyssynchrony (-83 ms vs. 1 ms, P<0.00001).
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