Key result
Patients with chronic pulmonary hypertension had significantly lower peak longitudinal right ventricular wall strain (-20.8% vs -28.0%, p<0.01) and delayed time-to-peak strain compared to individuals without pulmonary hypertension.
Why the study?
Does tissue Doppler imaging identify right ventricular dyssynchrony that correlates with disease severity in patients with chronic pulmonary hypertension?
Cross-Sectional (n=52)
No
Does tissue Doppler imaging identify right ventricular dyssynchrony that correlates with disease severity in patients with chronic pulmonary hypertension?
Absolute Event Rate: -20.8% vs -28%
p-value: p=<0.01
Tissue Doppler imaging can identify right ventricular dyssynchrony in patients with chronic pulmonary hypertension, which correlates strongly with echocardiographic markers of right ventricular dysfunction and clinical disease severity.
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RV dyssynchrony may link elevated PASP to symptoms and RV dysfunction in pulmonary hypertension; leaves open its role as a therapeutic target.
López‐Candales et al. (2005) conducted a cross-sectional in Chronic pulmonary hypertension (n=52). Chronic pulmonary hypertension vs. Individuals without pulmonary hypertension was evaluated on Peak longitudinal right ventricular wall strain (p=<0.01). Patients with chronic pulmonary hypertension had significantly lower peak longitudinal right ventricular wall strain (-20.8% vs -28.0%, p<0.01) and delayed time-to-peak strain compared to individuals without pulmonary hypertension.
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