Key result
Cardiac resynchronization therapy (CRT-D) significantly improved psycho-cognitive performance, including DemTect scores (P=0.007) and depression (P<0.001), compared to ICD therapy in CHF patients.
Why the study?
Does biventricular defibrillator (CRT-D) improve psycho-cognitive performance and depression symptoms in patients with congestive heart failure and severe left ventricular dysfunction compared to implantable single or dual-chamber defibrillator (ICD)?
Cohort (n=74)
Single-blind
Does biventricular defibrillator (CRT-D) improve psycho-cognitive performance and depression symptoms in patients with congestive heart failure and severe left ventricular dysfunction compared to implantable single or dual-chamber defibrillator (ICD)?
p-value: p=0.007
Cardiac resynchronization therapy significantly improves psycho-cognitive performance and depression symptoms in patients with heart failure and severe left ventricular dysfunction compared to standard ICD therapy.
No takes yet. Share an insight, caveat, or question.
CRT-D may confer psycho-cognitive benefits in heart failure; hypothesis-generating from observational data and requires randomized confirmation.
Duncker et al. (2015) conducted a cohort in Congestive heart failure (CHF) and severe left ventricular dysfunction (n=74). Biventricular defibrillator (CRT-D) vs. Implantable single or dual-chamber defibrillator (ICD) was evaluated on DemTect-score (p=0.007). Cardiac resynchronization therapy (CRT-D) significantly improved psycho-cognitive performance, including DemTect scores (P=0.007) and depression (P<0.001), compared to ICD therapy in CHF patients.
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