Key result
Improvement in left ventricular ejection fraction following cardiac resynchronization therapy was associated with enhanced cognitive outcomes at 3 months (P=0.031).
Why the study?
Does improved left ventricular function following cardiac resynchronization therapy improve cognitive outcomes in patients with moderate to severe heart failure?
Cohort (n=27)
Does improved left ventricular function following cardiac resynchronization therapy improve cognitive outcomes in patients with moderate to severe heart failure?
p-value: p=0.031
Improvement in left ventricular ejection fraction following cardiac resynchronization therapy is associated with enhanced cognitive outcomes at 3 months in patients with moderate to severe heart failure.
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LVEF gains after CRT may associate with cognitive stability in HF; hypothesis-generating and requires randomized confirmation.
Hoth et al. (2010) conducted a cohort in Moderate to severe heart failure (n=27). Improvement in left ventricular ejection fraction (LVEF) vs. Patients without LVEF improvement was evaluated on Change in cognition (p=0.031). Improvement in left ventricular ejection fraction following cardiac resynchronization therapy was associated with enhanced cognitive outcomes at 3 months (P=0.031).
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