Key result
The half-transition time of VO2 on-kinetics is near-linearly proportional to the absolute difference between phosphocreatine concentration during work and at rest.
Population
Skeletal muscle (review of physiological mechanisms and computer modeling of oxidative phosphorylation)
Design
Review
Authors
Loading...
May inform VO2 kinetics interpretation in exercise testing; leaves open validation in clinical cardiovascular cohorts.
The transition time of VO2 on-kinetics is a phenomenological parameter resulting from biochemical properties of the system, such as mitochondria content and parallel activation of ATP supply and usage, rather than a physical factor that causes changes in the system.
Korzeniewski et al. (2006) conducted a review in Oxygen uptake kinetics in skeletal muscle. The half-transition time of VO2 on-kinetics is near-linearly proportional to the absolute difference between phosphocreatine concentration during work and at rest.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: