Key result
Cardiac resynchronization therapy in patients with chronic heart failure significantly decreased mean pulmonary arterial pressure from 29.1 mmHg to 23.9 mmHg and increased cardiac output at 3 months.
Why the study?
Does biventricular pacing improve hemodynamic parameters and NYHA class in patients with chronic heart failure?
Observational (n=118)
No
Does biventricular pacing improve hemodynamic parameters and NYHA class in patients with chronic heart failure?
Absolute Event Rate: 23.9% vs 29.1%
p-value: p=<0.001
Biventricular pacing significantly improves NYHA functional class in patients with severe chronic heart failure and LBBB.
CRT-associated hemodynamic gains in chronic HF should not yet change practice; leaves open confirmation of clinical benefit in randomized trials.
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Ozábalová et al. (2010) conducted an observational in Chronic heart failure (n=118). Cardiac resynchronization therapy (biventricular pacing) vs. Baseline (pre-implantation) was evaluated on Mean pulmonary arterial pressure (MPA) at 3 months (p=<0.001). Cardiac resynchronization therapy in patients with chronic heart failure significantly decreased mean pulmonary arterial pressure from 29.1 mmHg to 23.9 mmHg and increased cardiac output at 3 months.
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