Key result
Persistent AF is linked to ~26 ms longer P wave duration than paroxysmal AF.
Why the study?
Functional and structural atrial changes that decrease conduction velocity and cause intra-atrial blocks in AF are manifested on ECG by P wave duration and morphology.
Does persistent atrial fibrillation affect P wave duration and morphology compared to paroxysmal atrial fibrillation?
Observational (n=50)
No
Does persistent atrial fibrillation affect P wave duration and morphology compared to paroxysmal atrial fibrillation?
Persistent atrial fibrillation is associated with prolonged P wave duration and morphological changes indicative of interatrial conduction block rather than left atrial hypertrophy.
Answers are grounded in this paper and cite their sources.
May aid noninvasive AF phenotyping on ECG; leaves open prospective validation for progression or therapy guidance.
Background: Functional and structural atrial changes contribute to AF. It decreases conduction velocity and forms intra atrial blocks. In the ECG those changes are manifested by the duration and morphology of the P wave. Material and methods: The study group consisted of 50 patients with atrial fibrillation. There were 27 women and 23 men, aged 65.3 +/-9.8 years. 22 patients had paroxysmal AF and 28 had persistent AF, in the latter direct current cardio version was performed. Results: In patients with a prolonged episodes of atrial fibrillation the P wave duration was longer in comparison to patients with sinus rhythm (187.1 +/-31.5 vs 161.1 +/-18.8 ms; p = 0.006). There were significant differences in P wave duration among the patients with normal and abnormal interatrial conduction, with the longest duration in complete Bachmann's bundle block group (152.7 +/-17.5 vs 165.3 +/-15.3 vs 207.9 +/-27.5 ms; p < 0.001). Conclusions: In patients with persistent atrial fibrillation the duration of the P wave is prolonged in comparison to paroxysmal. In the majority of patients prolongation of the P wave duration is dependent on different forms of conduction block. The morphological changes of P waves are caused by the arrhythmia rather than left atrial hypertrophy.
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Mercik et al. (2020) conducted an observational in Atrial fibrillation (n=50). Persistent atrial fibrillation vs. Paroxysmal atrial fibrillation was evaluated on P wave duration (ms) (p=0.006). Persistent atrial fibrillation was associated with a longer P wave duration compared to paroxysmal atrial fibrillation.
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