Key result
Global measures of ventricular dyssynchrony (total isovolumic time, P<0.001; difference between ventricular pre-ejection periods, P=0.025) independently predicted clinical response to CRT.
Why the study?
Do global measures of ventricular dyssynchrony predict clinical response to cardiac resynchronization therapy in patients with heart failure?
Cohort (n=39)
Do global measures of ventricular dyssynchrony predict clinical response to cardiac resynchronization therapy in patients with heart failure?
p-value: p=<0.001
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Global measures of ventricular dyssynchrony, such as total isovolumic time and the difference between ventricular pre-ejection periods, are independent predictors of clinical response to CRT.
Duncan et al. (2006) conducted a cohort in Heart failure (n=39). Cardiac resynchronization therapy (CRT) was evaluated on Fall in New York Heart Association (NYHA) class and increase in cardiac output (CO) (p=<0.001). Global measures of ventricular dyssynchrony (total isovolumic time, P<0.001; difference between ventricular pre-ejection periods, P=0.025) independently predicted clinical response to CRT.
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