Key result
Atrially-tracked ventricular pacing resulted in significantly lower peak VO2 (P<0.015) and oxygen pulse (P<0.01) compared to intrinsic conduction in patients with dual chamber pacemakers.
Why the study?
Does preserving intrinsic conduction improve cardiopulmonary performance compared to ventricular pacing in patients with dual chamber pacemakers?
RCT (n=13)
Random sequence
Does preserving intrinsic conduction improve cardiopulmonary performance compared to ventricular pacing in patients with dual chamber pacemakers?
p-value: p=<0.015
Preserving intrinsic conduction in patients with dual chamber pacemakers significantly improves peak oxygen uptake and oxygen pulse compared to unnecessary right ventricular pacing.
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Clinicians should minimize atrially-tracked ventricular pacing when intrinsic conduction is feasible; confirms benefits of conduction preservation for exercise performance in dual-chamber pacemaker patients.
Harper et al. (1991) conducted an RCT in Permanent AV sequential pacemakers (n=13). Atrially-tracked ventricular pacing vs. Intrinsic conduction was evaluated on Peak oxygen uptake (VO2) and oxygen pulse (O2P) (p=<0.015). Atrially-tracked ventricular pacing resulted in significantly lower peak VO2 (P<0.015) and oxygen pulse (P<0.01) compared to intrinsic conduction in patients with dual chamber pacemakers.
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