Population
Anesthetized open chest dogs
Design
Preclinical
Authors
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May refine vasodilator hemodynamics in experimental models; leaves open translation of three-type venous return classification to clinical practice.
Vasodilators affect systemic capacitance and resistance vessels differently, producing three distinct patterns of venous return curve changes, which can increase cardiac output even when mean circulatory pressure decreases.
Ito et al. (1984) studied this question.
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