Salt-Sensitive Hypertension Develops After Short-Term Exposure to Angiotensin II

Lombardi et al. (1999) studied Salt-sensitive hypertension. Angiotensin II (Ang II) followed by high salt diet (4% NaCl) vs. High salt diet with no prior Ang II exposure, or low salt diet (0.1% NaCl) after Ang II exposure was evaluated on Development of hypertension. Transient exposure to pressor doses of Angiotensin II followed by a high salt diet induced the redevelopment of hypertension in rats after 3 to 4 weeks, whereas control groups remained normotensive.

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