Key result
TyG index shows no link to MACCE in nondiabetic patients undergoing PCI.
Why the study?
Whether the triglyceride-glucose index is independently related to poor prognosis in nondiabetic patients undergoing PCI remained unclear.
Does the triglyceride-glucose (TyG) index predict major adverse cardiovascular and cerebrovascular events in nondiabetic patients undergoing percutaneous coronary intervention?
Population
5,489 nondiabetic patients who underwent PCI
Comparison
Three groups based on TyG index
Design
Cohort study
Follow-up
Median 29-month
Authors
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TyG index should not guide MACCE risk assessment in nondiabetic PCI patients; leaves open subgroup-specific utility.
Cohort (n=5,489)
No
Does the triglyceride-glucose (TyG) index predict major adverse cardiovascular and cerebrovascular events in nondiabetic patients undergoing percutaneous coronary intervention?
Effect estimate: HR 0.77 (95% CI 0.56-1.16)
p-value: p=0.210
The TyG index does not independently predict adverse cardiovascular outcomes in nondiabetic patients undergoing PCI, though it may have predictive value in the subgroup with LDL-C < 1.8 mmol/L.
Yang et al. (2021) conducted a cohort in Nondiabetic patients undergoing percutaneous coronary intervention (n=5,489). Triglyceride-Glucose (TyG) index vs. Lower TyG index tertiles was evaluated on Major adverse cardiovascular and cerebrovascular events (MACCE) (HR 0.77, 95% CI 0.56-1.16, p=0.210). The TyG index was not independently associated with major adverse cardiovascular and cerebrovascular events in nondiabetic patients undergoing percutaneous coronary intervention (HR 0.77, P=0.210).
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