Key result
Isolated AVN-FP ablation completely eliminated vagus trunk stimulation-induced sinus rate slowing, AF inducibility, and ERP shortening in dogs compared to baseline (all P < 0.05).
p-value: p=<0.05
No takes yet. Share an insight, caveat, or question.
May identify AVN-FP as ablation target for vagal AF; hypothesis-generating in canine model, human studies required.
Zhou et al. (2013) studied Atrial fibrillation and sinus node function (n=18). Sequential ablation of SAN-FP and AVN-FP vs. Prior to ablation (baseline) was evaluated on Sinus rate, AF inducibility, and ERP changes during electrical stimulation of the vagus trunk (p=<0.05). Isolated AVN-FP ablation completely eliminated vagus trunk stimulation-induced sinus rate slowing, AF inducibility, and ERP shortening in dogs compared to baseline (all P < 0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: