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May 26, 2023Open Access

AV node ablation and pacing improves symptoms and cardiac performance in refractory HF and AF.

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Why the study?

The study was conducted to review relevant literature on the use of atrioventricular node ablation and pacing in patients with heart failure and atrial fibrillation.

Does atrioventricular node ablation and pacing improve clinical outcomes in patients with heart failure and atrial fibrillation?

Population

Patients with heart failure and atrial fibrillation

Comparison

Atrioventricular node ablation and pacing modalities

Design

Literature review

Key result

Atrioventricular node ablation and pacing improves symptoms and cardiac performance in patients with heart failure and atrial fibrillation who are unresponsive or intolerant to medical treatment.

Authors

IKIoanna KoniariAGAndreas GerakarisNKNicholas G. Kounis

Discussion

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Member takes

Overview

Supports AV node ablation-pacing for refractory AF-HF symptoms; hypothesis-generating, needing RCTs for hard outcomes.

Structured PICO

Does atrioventricular node ablation and pacing improve clinical outcomes in patients with heart failure and atrial fibrillation?

P
Population
Patients with atrial fibrillation ± heart failure who do not respond or are intolerant to medical treatment
I
Intervention
Atrioventricular node ablation and pacemaker implantation (including cardiac resynchronization therapy, His bundle pacing, or left bundle branch pacing)
C
Comparator
Right ventricle apical pacing or medical treatment
O
Outcome
Clinical outcomes, symptoms, and cardiac performance

Atrioventricular node ablation combined with pacing (especially CRT or His bundle pacing) is an effective strategy for improving symptoms and cardiac performance in patients with AF and HF refractory to medical therapy.

Cite This Study

Koniari et al. (2023) conducted a review in Heart failure and atrial fibrillation. Atrioventricular node ablation and pacing vs. Right ventricle apical pacing or medical treatment was evaluated on Clinical outcomes and complications. Atrioventricular node ablation and pacing improves symptoms and cardiac performance in patients with heart failure and atrial fibrillation who are unresponsive or intolerant to medical treatment.

synapsesocial.com/papers/6a15d8bfbdb7c2566652248ehttps://doi.org/10.20944/preprints202305.1936.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outcomes of Atrioventricular Node Ablation and Pacing in Patients with Heart Failure and Atrial Fibrillation: From Cardiac Resynchronization Therapy to His Bundle Pacing2023 · 14 citations
  2. 2Complementary use of conduction system pacing techniques for the “pace and ablate” strategy in permanent atrial fibrillation - a case report2024
  3. 3His-Purkinje conduction system pacing and atrioventricular node ablation in treatment of persistent atrial fibrillation refractory to multiple ablation procedures: A case report2023 · 3 citations
  4. 4Pace and ablate: The ultimate treatment for atrial fibrillation?2020 · 1 citations
  5. 5Pace and ablate: The ultimate treatment for atrial fibrillation?2021