Key result
Off-pump CABG linked to a ~66% increase in coronary sinus blood flow.
Why the study?
Coronary artery revascularization increases coronary sinus blood flow, and measuring this with transesophageal echocardiography may help estimate revascularization adequacy during off-pump CABG.
Can transesophageal echocardiography measurement of coronary sinus blood flow estimate the adequacy of revascularization in patients undergoing off-pump coronary artery bypass grafting?
Observational (n=100)
Can transesophageal echocardiography measurement of coronary sinus blood flow estimate the adequacy of revascularization in patients undergoing off-pump coronary artery bypass grafting?
Absolute Event Rate: 363.8% vs 218.9%
p-value: p=<0.001
Transesophageal echocardiography measurement of coronary sinus blood flow provides a real-time, intraoperative method to evaluate the adequacy of surgical revascularization during off-pump CABG.
May support TEE coronary sinus flow as revascularization marker in off-pump CABG; leaves open clinical utility pending validation studies.
Introduction Revascularization of coronary artery increases the blood flow in the coronary sinus (CS) too. The study aimed to measure the CS blood flow using transesophageal echocardiography (TEE) to estimate the adequacy of revascularization in patients undergoing off-pump coronary artery bypass grafting.Patients and methods After ethical committee approval, 100 patients scheduled for elective coronary artery bypass grafting were included in this study. After induction of balanced anesthesia according to institutional protocol, a 5-Hz multiplane phased-array TEE probe was inserted into patients’ esophagus, and the following parameters were calculated at pre-revascularization and post-revascularization periods: velocity time integral of CS, coronary sinus diameter, coronary sinus cross-section area, and coronary sinus blood flow (CSBF) per beat and per minute.Results Our study showed a statistically significant increase in velocity time integral in the post-revascularization period as compared with the pre-revascularization period (P<0.001). There was significant increment in mean CS diameter in the post-revascularization period as compared with the pre-revascularization period (0.79 vs.0.68 cm) (P<0.001). There was a significant increase in CSBF per minute in the post-revascularization period (363.8±80.55 ml) as compared with the pre-revascularization period (218.9±46.61 ml) (P<0.001).Conclusion TEE is a superior modality to evaluate CSBF before and after coronary artery bypass revascularization to determine the adequacy of surgical revascularization in real time during off-pump coronary artery bypass revascularization.
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Gandhi et al. (2021) conducted an observational in Patients undergoing off-pump coronary artery bypass grafting (n=100). Off-pump coronary artery bypass grafting vs. Pre-revascularization was evaluated on Coronary sinus blood flow (CSBF) per minute (p=<0.001). Off-pump coronary artery bypass grafting significantly increased coronary sinus blood flow per minute from 218.9±46.61 ml pre-revascularization to 363.8±80.55 ml post-revascularization (P<0.001).
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