Key result
Coronary tortuosity index at end-diastole was higher in arterial hypertension (105.7%) than controls (104.1%, P<0.05) and aortic regurgitation (102.9%, P<0.001), indicating pressure overload effects.
Why the study?
Does chronic pressure or volume overload alter coronary artery tortuosity compared to controls?
Population
62 patients, including 16 controls, 14 patients with arterial hypertension, and 32 patients with aortic…
Comparison
Arterial hypertension and aortic regurgitation vs Controls
Design
Cross-sectional
Authors
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Coronary tortuosity may mark pressure but not volume overload; leaves open prognostic value and need for longitudinal studies.
Observational (n=62)
Does chronic pressure or volume overload alter coronary artery tortuosity compared to controls?
Absolute Event Rate: 105.7% vs 104.1%
p-value: p=<0.05
Coronary tortuosity is more pronounced in patients with chronic pressure overload than volume overload, and is determined by gender, age, left ventricular volume, and muscle mass.
Jakob et al. (1996) conducted an observational in Chronic pressure and volume overload (n=62). Arterial hypertension and aortic regurgitation vs. Healthy controls was evaluated on Tortuosity index (TI, %) at end-diastole (p=<0.05). Coronary tortuosity index at end-diastole was higher in arterial hypertension (105.7%) than controls (104.1%, P<0.05) and aortic regurgitation (102.9%, P<0.001), indicating pressure overload effects.
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