Key result
Older age is linked to ~6% higher odds of coronary artery tortuosity in chronic coronary syndrome.
Why the study?
Coronary artery tortuosity is a common finding that can cause myocardial ischemia without significant stenosis, prompting comparison of features between CCS patients with and without tortuosity.
What are the demographic, clinical, and echocardiographic predictors of coronary artery tortuosity in patients with chronic coronary syndrome?
Observational (n=361)
No
What are the demographic, clinical, and echocardiographic predictors of coronary artery tortuosity in patients with chronic coronary syndrome?
Odds Ratio: 1.059 (95% CI 1.032–1.087)
p-value: p=<0.001
Advanced age and hypertension are independent predictors of coronary artery tortuosity in patients with chronic coronary syndrome undergoing elective angiography.
Age and hypertension associate with tortuosity in chronic coronary syndrome; hypothesis-generating and should not yet change practice.
Aim Coronary artery tortuosity is a common coronary angiographic finding. This tortuosity can cause myocardial ischemia even in the absence of significant coronary artery stenosis. Our aim was to compare the demographic, clinical and echocardiographic features of patients with chronic coronary syndrome (CCS) and with and without coronary artery tortuosity.Material and methods 361 patients who underwent elective coronary angiography (CAG) due to CCS were included in the study. These patients divided into two groups, those with coronary tortuosity (Group 1) and those without (Group 2). Univariable and multivariable logistic regression analysis was performed to identify predictors associated with coronary artery tortuosity.Results The mean age of the 361 CCS patients (44 % female; 56 % male) was 56.7±11.5 years. In the univariable regression analysis, age, female sex, hypertension (HT), PR interval, QTc interval, ST / T segment changes, left ventricle diastolic dysfunction (LVDD), left ventricle hypertrophia (LVH) were identified as predictors of coronary tortuosity. In the multivariable regression analysis, age (OR: 1.059; 95 %CI: 1.032-1.087, p<0.001) and hypertension (OR: 0.484; 95 %CI: 0.278-0.843, p=0.01) were identified as independent predictors of coronary tortuosity.Conclusion Coronary artery tortuosity is an angiographic finding that develops as a result of adaptive mechanisms in the heart and can cause myocardial ischemia. Predictors of coronary artery tortuosity in patients with CCS were long PR and QTc intervals, ST / T segment changes, LVH, LVDD, advanced age, and female gender. Evaluation of these demographic, electrocardiographic, and echocardiographic data may help clinicans to anticipate coronary artery tortuosity in patients with CCS and to be precautious for PCI.
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Yurdam et al. (2023) conducted an observational in Chronic coronary syndrome (n=361). Advanced age and hypertension vs. Younger age and absence of hypertension was evaluated on Predictors of coronary artery tortuosity (OR 1.059, 95% CI 1.032-1.087, p=<0.001). Advanced age (OR 1.059) and hypertension (OR 0.484) were identified as independent predictors of coronary artery tortuosity in patients with chronic coronary syndrome.
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