Key result
A typical echocardiographic left bundle branch block contraction pattern significantly predicted a positive response to cardiac resynchronization therapy compared to an atypical pattern (96% vs 21.4% response rate, p=0.001).
Why the study?
The study assessed the value of combining electrocardiographic variants and echocardiographic manifestations of LBBB to predict response to cardiac resynchronization therapy.
Does the combination of strict LBBB ECG criteria and typical echocardiographic contraction pattern predict response to cardiac resynchronization therapy in patients with heart failure and LBBB?
Population
39 patients with sinus rhythm, LBBB, QRS duration ≥130 ms, LVEF ≤35%, and NYHA II-IV HF
Comparison
Strict Strauss LBBB criteria vs other ECG variants
Design
Observational cohort study
Follow-up
6 months
Authors
Loading...
Typical LBBB strain pattern associated with CRT response; hypothesis-generating for refined selection, needs prospective validation.
Observational (n=39)
No
Does the combination of strict LBBB ECG criteria and typical echocardiographic contraction pattern predict response to cardiac resynchronization therapy in patients with heart failure and LBBB?
Absolute Event Rate: 96% vs 21.4%
p-value: p=0.001
The combination of strict LBBB ECG criteria and typical echocardiographic contraction pattern using longitudinal strain strongly predicts echocardiographic response to cardiac resynchronization therapy.
Kashtanova et al. (2018) conducted an observational in Heart failure with left bundle branch block (n=39). Typical LBBB echocardiographic contraction pattern vs. Atypical LBBB echocardiographic contraction pattern was evaluated on Response to CRT (decrease in LV end-systolic volume by >15%) (p=0.001). A typical echocardiographic left bundle branch block contraction pattern significantly predicted a positive response to cardiac resynchronization therapy compared to an atypical pattern (96% vs 21.4% response rate, p=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: